Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. The new Bristol-Myers Squibb research site in Cambridge’s Kendall Square will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation and business opportunities. Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Mechanisms of Cancer Resistance Thematic Research Center at BMS is one of the fundamental research and development engines delivering oncology therapeutics to patients. The scientists at this state-of-the-art research and development site in Cambridge focus on novel tumor intrinsic targets and pathways for tumors that are refractory to current Immuno-Oncology and Oncology therapies, and implement our discovery platforms across all of our therapeutic areas of focus. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of cancer biology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

We are seeking a highly motivated and independent Sr. Scientist to join the Oncology Discovery Pharmacology and In Vivo Biology Group at the Mechanisms of Cancer Resistance Thematic Research Center at Bristol-Myers Squibb in Cambridge, MA. This position will aide in the discovery and advancement of novel therapeutics for the treatment of cancer leveraging both cancer intrinsic and immune intrinsic biology.

The qualified candidate is a highly motivated, collaborative, and innovative in vivo and bench scientist who can conduct experiments utilizing tumor xenograft and genetically engineered mouse models to advance oncology discovery programs into the clinic. The qualified candidate is proficient at independently running in vivo oncology studies including model development, PK/PD, and anti-tumor efficacy. The ideal candidate should be proficient in executing ex vivo assays to investigate target engagement, mechanism of action and biomarkers by qPCR, ELISA (MSD), and WB. The successful candidate will demonstrate clear and professional communication, effectively collaborate with colleagues across a highly matrixed environment, and be capable of presenting scientific results to project teams. This role will lead from the bench, with opportunities to present data at team meetings

This position will be located at the new Bristol-Myers Squibb research site in Cambridge Crossing, a 480,000 square-foot state of the art Research and Early Development center that will help us continue to deliver on our mission and positions the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

Basic Qualifications:

• Bachelor’s Degree

  • 7+ years of academic and / or industry experience

Or

• Master’s Degree

  • 5+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

  • 2+ of academic and / or industry experience

Preferred Qualifications:

• Highly experienced at independently running xenograft mouse studies including model development, PK/PD, anti-tumor efficacy, and combination studies in conjunction with necropsy/tissue/blood collection across multiple projects with delivery of high-quality data.

• Skilled at murine dosing via PO, IP, IV, and SC routes.

• Demonstrated record of leveraging in vivo pharmacology models to explore cancer biology and enable cancer drug discovery. Experience developing and working with complex in vivo models, such as xenograft, patient derived xenograft (PDX), syngeneic and GEM models.

• Proficiency in cell culture, passaging and harvesting cells is required.

• Demonstrated experience with multi-parameter flow cytometry to investigate immune function of tumor infiltrating lymphocytes.

• Demonstrated experience executing ex vivo assays to investigate target engagement, mechanism of action and biomarkers by qPCR, ELISA (MSD), WB.

• Proficient in using software to analyze data and generating figures including GraphPad Prism, Electronic lab notebooks, Microsoft Office, etc.

• Exceptional attention to detail with excellent organizational and record keeping skills is required.

• Ability to work collaboratively across departments, understand and implement applicable regulations around animal care/safety/handling is required.

• Strong written and verbal communication skills with the ability to interact effectively with peers and management. Capable of presenting scientific results to multidisciplinary teams and key stakeholders.

• Highly motivated and demonstrated ability to be flexible in case of changing priorities. Ability to mentor junior associates and colleagues on best practices in the laboratory.

• This position is located in Cambridge, MA.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.